NEWS RELEASE

COPPELL, Texas, Jul 22, 2010 (BUSINESS WIRE) --

The International Sport Karate Association (ISKA) recently selected Mannatech(NASDAQ: MTEX) as its exclusive dietary supplement provider. The announcement was made at ISKA's 37^th annual U.S. Open, which featured more than 3,000 of the top martial artists from 40 participating countries and will be nationally televised on ESPN2 tomorrow, July 23,at9 p.m. ET/6 p.m. PT.

"For the first time in the 25-year history of ISKA, we are happy to announce our partnership with Mannatech and share it with our more than 28,000 studio owners," said Cory Schafer, president of ISKA.

"Third party certification by reputable organizations means Mannatech products have achieved a very rare level of purity, safety and trust," said Robert A. Sinnott, Ph.D., MNS, co-CEO and chief science officer of Mannatech. "Many of our products are already certified Kosher and certified for GMP compliance by NSF International, but we believe having products certified by the ISKA governing body confirms the benefits our supplements have for elite athletes and others who are very particular about what they put into their bodies."

The partnership will allow various Mannatech products to carry the 'ISKA Certified for Elite Athletes' seal, as well as a proven business-building opportunity for all studio owners represented by ISKA.

Present at the U.S. Open in Orlando were elite martial arts practitioners and Team Mannatech^SM athletes Chip Townsend and Ben Parra¹ who each set world records.

"Because of the variety of products offered in stores today, students often get confused with what nutritional supplements to take," said Townsend. "This partnership will take the guesswork out of the purchase because Mannatech products are developed with real food technologysolutions and without any banned substances."

Replay dates of the ISKA U.S. Open will air on ESPN2, August 19 and 22 at 9 p.m. ET/6 p.m. PT.

For more information about ISKA, visit www.ISKA.com. For more information about the partnership, Mannatech's products or business opportunity, visit www.Mannatech.com.

About Mannatech

Mannatech, Incorporated, develops high-quality health, weight and fitness, and skin care products that are based on the solid foundation of nutritional science and development standards. These proprietary products are available through independent sales Associates around the globe including the United States, Canada, South Africa, Australia, New Zealand, Austria, Denmark, Germany, Norway, Sweden, the Netherlands, the United Kingdom, Japan, Taiwan, Singapore and the Republic of Korea. For more information, visit www.Mannatech.com.

Please Note: This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by use of phrases or terminology such as "intend" or other similar words or the negative of such terminology. Similarly, descriptions of Mannatech's objectives, strategies, plans, goals or targets contained herein are also considered forward-looking statements. Mannatech believes this release should be read in conjunction with all of its filings with the United States Securities and Exchange Commission and cautions its readers that these forward-looking statements are subject to certain events, risks, uncertainties, and other factors. Some of these factors include, among others, Mannatech's inability to attract and retain associates and members, increases in competition, litigation, regulatory changes, and its planned growth into new international markets. Although Mannatech believes that the expectations, statements, and assumptions reflected in these forward-looking statements are reasonable, it cautions readers to always consider all of the risk factors and any other cautionary statements carefully in evaluating each forward-looking statement in this release, as well as those set forth in its latest Annual Report on Form 10-K and Quarterly Report on Form 10-Q, and other filings filed with the United States Securities and Exchange Commission, including its current reports on Form 8-K. All of the forward-looking statements contained herein speak only as of the date of this release.

¹ Team Mannatech athletes receive free Mannatech products. Some Team Mannatech athletes are also independent sales Associates.

SOURCE: Mannatech, Incorporated

for Mannatech, Incorporated
Shawn Paul Wood, 972-499-6614
Shawn.Wood@hck2.com