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New Independent Study of Mannatech Sports Drink Shows Significant
Improvements in Oxygen Consumption, Time to Exhaustion*
EM-PACT(R) Sports Drink "Provides Possible Alternative Hydration Options" for Coaches, Athletes

COPPELL, Texas, Jun 22, 2010 (BUSINESS WIRE) --Mannatech, Incorporated (NASDAQ: MTEX), a global pioneer in the development of high-quality health, weight and fitness, and skin care solutions based on nutritional science, announced the results of a recent randomized, double-blind, placebo-controlled, crossover trial that investigated the effect of its reformulated creatine-free EM-PACT(R)sports drink.

When EM-PACT drink mix was first studied in 2006, the authors concluded that the Mannatech sports supplement could "provide meaningful practical applications for coaches and athletes regarding possible alternative hydration options" prior to aerobic workouts.1 The published study was indexed by PubMed.gov, the medical literature search engine most commonly used by health care providers and sponsored by the U.S. Department of Health & Human Services' National Institutes of Health.

Four years later, this new independent study shows that a single serving of a revised formulation of the EM-PACT sports drink provides the same benefits as the original formulation--enhancing indices of aerobic performance. The product significantly increased maximal oxygen consumption, time to exhaustion and percentage of estimated non-protein fat substrate utilization of the college students who took part in the study. Estimated non-protein substrate utilization in this study indicated that energy was obtained from the burning of fat, rather than carbohydrates within the muscle during exercise. Associate Professor of Kinesiology at Angelo State University Dr. Allyn Byarspublished both the 2006 and 2010 findings in the Journal of the International Society of Sports Nutrition.2

"This study performed by Dr. Byars, an expert in the field of exercise physiology, confirms that Mannatech's creatine-free EM-PACT product, which meets the compliance standards of various athletic organizations that regulate the use of dietary supplements, is as effective as the original formulation," said Robert A. Sinnott, MNS, Ph.D., co-chief executive officer and chief science officer of Mannatech. "The enhanced aerobic performance noted with the study participants shows that anyone interested in improving their athletic performance should consider including the EM-PACT productin their workout regimen." *

This study, funded by Mannatech, included 29 male and female college students who varied in levels of aerobic fitness. Dr. Byars performed a randomized crossover administration EM-PACT drink mix and placebo 30 minutes prior to performing a treadmill test with approximately one week separation between the trials in an effort to measure affects on maximal oxygen consumption and heart rate, time to exhaustion and the percentage of estimated non-protein fat substrate utilization.

Its conclusion was the modified EM-PACT drink mix formulation utilized in this investigation supports the findings of the previous investigation and its efficacy for enhancing indices of aerobic performance (specifically maximal oxygen consumption, time to exhaustion and fat substrate) during graded exercise testing.

"Placebo-controlled, human clinical studies such as this one from Dr. Byars are the gold standard in nutritional research. They validate Mannatech's commitment to science and Real Food TechnologySM solutions," said Sinnott. "As the pioneer of nutritional glycobiology and supporter of athletics globally, we will continue to be a leader in the field of validated sports nutrition."

The newly formulated creatine-free EM-PACT drink mix will be available from Mannatech in July.

Many of Mannatech's products are based on Real Food Technology solutions, which provide consumers with products that contain standardized levels of natural and plant-sourced nutrients. Food-sourced ingredients are chosen from those scientifically proven to most benefit the human body. Mannatech offers the best alternative to synthetic vitamin and mineral products and so-called "super-juice" products.

In 1994, Mannatech founded theTeam MannatechSMprogram, a group of 195 athletes worldwide who utilize cutting-edge training techniques and proper nutrition while serving as educators preserving the integrity of sports competition and the health of all athletes.

Athletes interested in learning more about the Team Mannatech program can visit www.TeamMannatech.com. For more information about Mannatech's scientific research and findings, visit www.MannatechScience.org. Individuals interested in Mannatech's products or in exploring its business opportunity can learn more atwww.Mannatech.com.

About Mannatech

Mannatech, Incorporated, develops high-quality health, weight and fitness, and skin care products that are based on the solid foundation of nutritional science and development standards. These proprietary products are available through independent sales Associates around the globe including the United States, Canada, South Africa, Australia, New Zealand, Austria, Denmark, Germany, Norway, Sweden, the Netherlands, the United Kingdom, Japan, Taiwan, Singapore and the Republic of Korea. For more information, visit www.AllAboutMannatech.com.

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

1 This study consisted of 24 volunteers who performed two, one-hour oxygen consumption tests on motor-driven treadmills and 20 minutes prior, were given either a placebo or EM-PACT

2 Byars A., et al., 3[1]:56 - 59, 2006; Byars A., Keith S., Simpson W., Mooneyhan A., Greenwood M: The influence of a pre-exercise sports drink (PRX) on factors related to maximal aerobic performance. J Int Soc Sports Nutr 2010, 7:1-6.

SOURCE: Mannatech, Incorporated

Mannatech, Incorporated
Allison Lowe, 972-499-6631
allison.lowe@hck2.com