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Study Finds Mannatech’s Ambrotose® Complex Significantly Improves Visual Discrimination and Working Memory in Healthy Young Adults

Results of study published in the journal “Perceptual & Motor Skills”

(COPPELL, Texas) April 21, 2009 – Mannatech, Incorporated (NASDAQ – MTEX) today announced the results of a study, showing that a single one‐tablespoon serving of Ambrotose® complex significantly improved visual discrimination and working memory (1).
Drs. Atiya N. Stancil and Leslie H. Hicks, both of Howard University in Washington, D.C., published the randomized, double‐blind, placebo‐controlled study investigating the impact of Ambrotose complex on the brain function of 62 healthy young adults.

“The results of this study are impressive because they show significant improvement in the perceptual capabilities of healthy adults, which indicates that Ambrotose complex can benefit everyone,” said Dr. Stancil.

Dr. Robert A. Sinnott, MNS, chief science officer and senior vice president of Mannatech, heads Mannatech’s Research Group and developed previous double‐blind, placebo‐controlled clinical trials have demonstrated that ingestion of Ambrotose complex can enhance brain waves associated with attention or alertness (2), enhance concentration and improve mental reaction time (3), and improve memory (4).

“Drs. Stancil and Hicks’ study adds to the body of evidence that shows genuine effects of Ambrotose product in healthy adults,” said Dr. Sinnott. “It also confirms the positive cognitive results seen in other studies conducted in the United States and Australia.”

Mannatech – a leading developer and provider of proprietary dietary supplements, weight management products and skin care solutions – recently launched, which offers extensive resources explaining the science behind its proprietary product lines.

Mannatech’s Research Group is devoted to pre-clinical and clinical testing of products and product ingredients. To more effectively meet research goals, Mannatech collaborates with researchers around the world. Many of the publications that report the results of these studies are posted in the Peer-Reviewed Science section of its science Web site.

Mannatech donated the product used in this study, which was published in Perceptual & Motor Skills, a journal indexed by PubMed, the premier literature search tool for scientists and physicians.

(1) Stancil AN, Hicks LH. Glyconutrients and perception, cognition, and memory. Perceptual Motor Skills 2009; 10:259‐270.
(2) Wang C, Szabo JS, Dykman RA. Effects of a carbohydrate supplement upon resting brain activity. Integr Physiol Behav Sci 2004; 39(2):126‐138.
(3) Wang C, Pivik RT, Dykman RA. Effects of a glyconutritional supplement on brain potentials associated with language processing. Federation Proceedings: Experimental Biology Meeting, New Orleans, Louisiana, April 20‐24. 1‐4. 4‐20‐2002.
(4) Best T, Kemps E, Bryan J. The impact of saccharide supplementation on cognition and mood in middle‐aged adults. Presented at the 36th Annual International Neuropsychological Society Meeting, February 69, 2008, Waikoloa, Hawaii 2008.

About Mannatech
Mannatech, Incorporated, is a global wellness solutions provider of innovative, high-quality, proprietary dietary supplements, weight management products and skin care solutions sold through independent Associates and Members located in the United States and the international markets of Canada, Australia, the United Kingdom, Japan, New Zealand, the Republic of Korea, Taiwan, Denmark, Germany, South Africa, and Singapore. For more information, visit


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